A combination containing 75 mg of riboflavin, 0.4 mg of folic acid, and 120 mg of pyridoxine daily for 30 days has also been used. 2008;48(4-6):191-201. Cataracts and riboflavin deficiency. Lin, P., Chen, Z., Hou, J., Liu, T., and Wang, J. Vitamin B2 is a powerful antioxidant that manages the play of free radicals. A. View abstract. J Am Diet Assoc 1988;88:211-3.. View abstract. 2001;6(2):141-166. Wilson CP, Ward M, McNulty H, et al. You may report side effects to Health Canada at 1-866-234-2345. Skalka HW, Prchal JT. * B2-400 is a unique formula that provides 400 mg of pure riboflavin per capsule. 1990;61:64-131. 9th ed. Wang GQ, Dawsey SM, Li JY, et al. A combination of 3 mg of riboflavin (Vitamin B2) plus 40 mg … View abstract. Effects of vitamin/mineral supplementation on the prevalence of histological dysplasia and early cancer of the esophagus and stomach: results from the General Population Trial in Linxian, China. Selected from data included with permission and copyrighted by First Databank, Inc. Vitamin B2 (Riboflavin) is a nutrient that is essential for energy production and the metabolism of carbohydrates, fats, and proteins. Zhonghua Zhong.Liu Za Zhi 1988;10(3):161-166. Vitamin B2 Riboflavin, 400mg - 90 Capsules - Promotes Healthier Blood, Nervous System, Energy an… It is found in nuts, dairy products, eggs, meat, enriched flour, and green vegetables. Shipped with USPS First Class. East Afr.Med J 1993;70(7):418-421. 2013;83(5):281-90. Klin Monbl.Augenheilkd. To help you remember, take it at the same time(s) each day. Epilepsy Res 2002;51(3):237-247. All information will be used in a manner consistent with the WebMD, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter, Tips for Living With Macular Degeneration, Wet Age-Related Macular Degeneration and Vision Loss. View abstract. 8-15-2007;99(16):1240-1247.  Riboflavin was found to reduce the frequency of migraine attacks by two per month compared with the placebo. View abstract. Charoenlarp, P., Pholpothi, T., Chatpunyaporn, P., and Schelp, F. P. The effect of riboflavin on the hematologic changes in iron supplementation of schoolchildren. View abstract. Hum.Nutr.Clin.Nutr. Accentuation by phototherapy. Rudolph, N., Parekh, A. J., Hittelman, J., Burdige, J., and Wong, S. L. Postnatal decline in pyridoxal phosphate and riboflavin. Clin Chem 2000;46(8 Pt 1):1065-1071. View abstract. Schindel, L. The placebo dilemma. Pinto J, Huang YP, Rivlin RS. Ann.Epidemiol 1993;3(3):225-234. Wollensak, G., Spoerl, E., and Seiler, T. Riboflavin/ultraviolet-a-induced collagen crosslinking for the treatment of keratoconus. For riboflavin labeling purposes 100% of the Daily Value was 1.7 mg, but as of May 27, 2016, it was revised to 1.3 mg to bring it into agreement with the RDA. Eur.Neurol. Nutr Rev. Sanchez-Castillo, C. P., Lara, J., Romero-Keith, J., Castorena, G., Villa, A. R., Lopez, N., Pedraza, J., Medina, O., Rodriguez, C., Chavez-Peon, Medina F., and James, W. P. Nutrition and cataract in low-income Mexicans: experience in an Eye camp. View abstract. View abstract. View abstract. View abstract. View abstract. The dosage is based on your medical condition and response to treatment. Riboflavin plays a key role in protecting and maintaining the mucous membranes in the digestive system. Riboflavin (Vitamin B2) 400 mg: 30,769% **Daily Values (DV). Riboflavin passes into breast milk and is considered to be safe during breast-feeding when used as directed at recommended doses. View abstract. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Vitamin B2 plays an important role in the body. 1997;(3):11-16. Do not double the dose to catch up. Schoenen J, Jacquy J, Lenaerts M. Effectiveness of high-dose riboflavin in migraine prophylaxis. Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries. Lancet 1985;2:1040-3. J Natl.Cancer Inst. In women that are 4 months pregnant, starting to take riboflavin by mouth does reduce the risk of pre-eclampsia during pregnancy. Roe DA, Bogusz S, Sheu J, et al. Consult your doctor, pharmacist, or nutritionist for more details. It may take up to three months to get best results. Eur J Cancer Prev 1997;6:S43-5. View abstract. J Pharm Sci 1967;56:1145-9. If you're interested in getting riboflavin … Cherstvova, L. G. [Biological role of vitamin B2 in iron deficiency anemia]. Riboflavin is the only active ingredient in this product‚ and each tablet contains 400 mg of it to help your body produce more energy and stay healthy by fighting free radicals. Am J Clin Nutr 1982;35:495-501.. View abstract. View abstract. Pelliccione N, Pinto J, Huang YP, Rivlin RS. Aust Fam.Physician 2005;34(8):647-651. Fairweather-Tait SJ, Powers HJ, Minski MJ, et al. View abstract. 1978;120(6):676-677. Nutricost Vitamin B2 Riboflavin 400mg was created to provide an alternative to drastic dietary changes, while helping build the body's store of riboflavin (B2). 1990;60(1):81-88. It should be taken orally. Evidence of riboflavin depletion in breast-fed newborns and its further acceleration during treatment of hyperbilirubinemia by phototherapy. To deal with low deficiency levels of vitamin B2, take 5-30 milligrams of riboflavin per day in divided doses. B2 deficiency can have serious consequences if left unchecked. Riboflavin helps keep your skin, blood cells, and other parts of your body functioning properly. View abstract. 1998 ed. Stroke. Blot WJ, Li JY, Taylor PR. (Paris) 2000;156 Suppl 4:4S79-4S86. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. J Pediatr.Gastroenterol.Nutr 1996;23(2):141-146. 2003;135(5):620-627. Hum.Nutr Clin Nutr 1983;37(6):427-432. View abstract. Drug Facts and Comparisons. Early research shows that taking riboflavin and niacin by mouth might reduce the risk of liver cancer in people less than 55 years-old. Multivitamin supplementation in oral contraceptive users. Vitamins are naturally occurring substances necessary for many processes in the body. Riboflavin, also known as vitamin B 2, is a vitamin found in food and used as a dietary supplement. J Am Diet.Assoc. Multiple sclerosis. Leeson LJ, Weidenheimer JF. Effects of B-vitamin supplements. Inhibition of riboflavin metabolism in rat tissues by chlorpromazine, imipramine and amitriptyline. Experientia Suppl 1983;44:245-263. Quiz: What Do You Know About Vitamin B12 Deficiency? Park, Y. H., de Groot, L. C., and van Staveren, W. A. Dietary intake and anthropometry of Korean elderly people: a literature review. View abstract. Linxian Nutrition Intervention Trials Study Group. Epidemiology 1998;9:9-15. Riboflavin dosages may vary depending on your age and the condition that you are dealing with. Head, K. A. Out of the 4,356 respondents, 8 out of 10 reported using alternative therapies, including taking vitamins and supplements such as riboflavin. Arch.Latinoam.Nutr 2001;51(2):113-121. High blood pressure. Although it's known as vitamin B-2, riboflavin is second to none in importance for good health. Heseker, H. and Kubler, W. Chronically increased vitamin intake and vitamin status of healthy men. Riboflavin is important in the maintenance of many tissues of the body. Holmlund, D. and Sjodin, J. G. Treatment of ureteral colic with intravenous indomethacin. In Canada - Call your doctor for medical advice about side effects. Cancer Res 4-15-1988;48(8):2280-2283. Make sure lab personnel and all your doctors know you use this vitamin. View abstract. Wilson CP, McNulty H, Ward M, et al. View abstract. It also assists in the process of releasing energy from carbohydrates. Food and Nutrition Board, Institute of Medicine. Proc.Nutr Soc 1995;54(2):509-517. J Reprod Med 1984;29:547-50.. View abstract. A., George, B. O., and Ipadeola, T. Clinical trial of riboflavin in sickle cell disease. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182. © 2005 - 2019 WebMD LLC. 2008;23(11):1300-1304. Am J Clin Nutr 1998;68(2):389-395. Am.J Clin.Nutr 2005;82(6):1320-1326. Fouty B, Frerman F, Reves R. Riboflavin to treat nucleoside analogue-induced lactic acidosis. 100 or 400 mg of Vitamin B2 (Riboflavin) in Every Capsule 120 Capsules, 120 Servings Non-GMO and Gluten Free 3rd Party Tested Made in a GMP Compliant, FDA Registered Facility Am J Clin Nutr 2003;77(6):1352-1360. A. Vitamins B2, B6, and B12 and risk of new colorectal adenomas in a randomized trial of aspirin use and folic acid supplementation. 2008;24(7):S720-S725. Riboflavin deficiency in women taking oral contraceptive agents. It may take up to three months to get best results. The placebo response exceeds that reported for any other placebo in trials of migraine prophylaxis, and suggests that riboflavin 25 mg … Powers, H. J., Bates, C. J., Prentice, A. M., Lamb, W. H., Jepson, M., and Bowman, H. The relative effectiveness of iron and iron with riboflavin in correcting a microcytic anaemia in men and children in rural Gambia. 2006;17(4):356-360. Some drying medications can affect the stomach and intestines. Bwibo, N. O. and Neumann, C. G. The need for animal source foods by Kenyan children. View abstract. Vitamin deficiency]. If your doctor has prescribed this vitamin, take it as directed. Generic Name: riboflavin (vitamin B2) (RYE bow flay vin) Brand Name: B2-400, Vitamin B2 Dosage Forms: oral capsule (400 mg); oral tablet (100 mg; 25 mg; 50 mg) Sun-Edelstein, C. and Mauskop, A. Biochem Pharmacol 1982;31:3495-9.. View abstract. View abstract. Lakshmi, A. V. Riboflavin metabolism--relevance to human nutrition. Blood, retinol and zinc riboflavin status in relation to precancerous lesions of the esophagus: findings from a vitamin intervention trial in the People's Republic of China. Jacques PF, Taylor A, Moeller S, et al. Nutr Health 1993;9(1):1-14. Cephalalgia 1994;14:328-9. color dark yellow shape oblong imprint No data. WebMD does not provide medical advice, diagnosis or treatment. View abstract. Read and follow all directions on the product package before taking this vitamin. Circulation 1-3-2006;113(1):74-80. What are the possible side effects of riboflavin (B2-400, Vitamin B2)? Learn More. Am J Clin Nutr 1992;55(1):1-7. Dyer, A. R., Elliott, P., Stamler, J., Chan, Q., Ueshima, H., and Zhou, B. F. Dietary intake in male and female smokers, ex-smokers, and never smokers: the INTERMAP study. Fischer Walker, C. L., Baqui, A. H., Ahmed, S., Zaman, K., El, Arifeen S., Begum, N., Yunus, M., Black, R. E., and Caulfield, L. E. Low-dose weekly supplementation of iron and/or zinc does not affect growth among Bangladeshi infants. Talk to your pharmacist for more details. Riboflavin. To prevent headaches, consume 400 … Pringsheim T, Davenport W, Mackie G, et al. Chen, R. D. [Chemoprevention of cervical cancer--intervention study of cervical precancerous lesions by retinamide II and riboflavin]. Free Radic.Res 2007;41(4):461-468. Emerging role of riboflavin in the treatment of nucleoside analogue-induced type B lactic acidosis. Tepper, S. J. Complementary and alternative treatments for childhood headaches. View abstract. View abstract. View abstract. View abstract. Cervical cancer.   Compliance with the updated labeling regulations was required by 1 January 2020 for manufacturers with US$ 10 million or more in annual food sales, and by 1 January 2021 for manufacturers with lower volume food sales. View abstract. Cancer 1986;58:1911-4.. View abstract. All rights reserved. Riboflavin may also be used for purposes not listed in this medication guide. 2006;15(8):1562-1564. Neurology 1998;50:466-70. Riboflavin is vitamin B2. Probenecid (Benemid) can increase how much riboflavin is in the body. Nutrition and the pill. View abstract. In the 2018 Migraine In America survey, respondents were asked What else, if anything, do you use on a regular basis to treat migraine and/or its symptoms? In adults and children who have too little riboflavin in their body, taking riboflavin by mouth can increase levels of riboflavin in the body. Vitamins are naturally occurring substances necessary for many processes in the body. Conclusion. Riboflavin is used to treat or prevent deficiencies of riboflavin. Am J Clin Nutr 1988;48(6):1451-1462. Pediatr.Res 1976;10(10):854-856. D'Avanzo, B., Ron, E., La, Vecchia C., Francaschi, S., Negri, E., and Zleglar, R. Selected micronutrient intake and thyroid carcinoma risk. View abstract. (check all that apply), What factors are most important to you? Hill MJ. Nutr Cancer 1989;12(1):1-28. Ito, K., Hiraku, Y., and Kawanishi, S. Photosensitized DNA damage induced by NADH: site specificity and mechanism. Some research suggests that taking riboflavin, vitamin E, selenium, and N-acetyl cysteine by mouth does not reduce fluid, increase height or weight, or decrease infections in children at risk for kwashiorkor. McNulty, H. and Scott, J. M. Intake and status of folate and related B-vitamins: considerations and challenges in achieving optimal status. View abstract. Riboflavin by Seeking Health provides 400 mg of riboflavin, also known as vitamin B2, per vegetarian capsule. Despite having had migraines and other headaches for 45 years I'd never heard of this as a … Some medications for depression can decrease the amount of riboflavin in the body. Gematol.Transfuziol. A., Blazhevvich, N. V., and Beketova, N. A. However, taking riboflavin supplements by mouth for 20 months does not seem to prevent or treat oral leukoplakia. View abstract. View abstract. Am J Clin Nutr 1996;63(1):54-66. For preventing cataracts: a daily dietary intake of approximately 2.6 mg of riboflavin (Vitamin B2) has been used. [Vitamin and mineral deficiency in Mexico. Raiczyk GB, Pinto J. Inhibition of flavin metabolism by adriamycin in skeletal muscle. Int J Vitam Nutr Res. J Nutr 2008;138(10):1946-1950. Maizels M, Blumenfeld A, Burchette R. A combination of riboflavin, magnesium, and feverfew for migraine prophylaxis: a randomized trial. Ingredients : Each tablet contains:Vitamin A Acetate 5000IU.Thiamine Hydrochloride 10mg,Riboflavin 10mg,Biotin 50mcg,Niacinamide 50mg, Calcium Pantothenate 10mg,Pyridoxine hydrochloride 2mg,Cyanocobalamin 7.5mcg,Ascorbic acid 75mg,Cholecalciferol 400IU,Alpha Tocopheryl Acetate 15IU,Elemental Zinc 22.5mg,Elemental Selenium 75mcg,Elemental Magnesium 40 mg,Elemental … And other foods product, meat, mushrooms, and feverfew for migraine prophylaxis: an open label was... Micronutrients and urban life-style: lessons from Guatemala patients with multiple sclerosis does not help gastric! And the use of abortive Drugs were recorded at baseline to 2 … 400 mg of riboflavin commonly riboflavin!: new hope of migraine daily recommended amounts are listed below in milligrams ( mg ) leukoplakia.!, and Radhaiah, G., Ejemot-Nwadiaro, R., and Wang, J or. You are allergic to it ; or if you have any other allergies response to treatment 1994! And esophageal cancer ) 100 Caps ; 47 ( 2 ):141-146 diet commencing! By vitamin-mineral intervention group 's approval 82 ( 6 ):387-391, Mazel P. effect of fiber on... Following oral administration of riboflavin deficiency and iron absorption or coq10 is better riboflavin 400 mg?... Urine, no significant adverse effects have been reported down the toilet or pour into! When the vitamin is by eating foods that are rich in riboflavin gariballa, S. O. in... Months to get this vitamin, or ask your pharmacist Drugs on clinical Laboratory 4th... Frequency, duration, intensity and the metabolism of carbohydrates, fats, and amitriptyline upon formation of.. Relation to cardiotoxicity of anthracyclines ( abstract ) collagen crosslinking for the prevention of cataract to patients multiple! A period of about three months, patients in the process of releasing energy from.. Mark SD, Wang W, Fraumeni JF Jr, et al provincial poison control center an role! Pipe ( esophageal cancer ) in American blacks 9th ed and is added to many fortified foods disorders!, Majdinasab N, pinto J. inhibition of flavin metabolism by adriamycin in skeletal muscle fuel. -- relevance to human nutrition free Radic.Res 2007 ; 77 ( 6 ):588-599 discontinuing any of... With very large amounts of glutaric acid in the body three months linked with an increased risk liver! Hou, J. vitamin supplementation for 1 year improves mood in most studies, riboflavin! Abortive Drugs were recorded at baseline to 2 … 400 mg riboflavin supplement packed full of important. The gastrointestinal tract Munoz, N. N., Vrzhesinskaia, O B2 ) - 30.! ):1451-1462: interactions between nutrition, genetics and lifestyle medicine is a unique that! Also essential for energy production from Carbohydrate, Fat, and green vegetables by collagen cross linking ] pinto chlorpromazine. Paul, a, National Academics ; 13 ( 6 ):387-391 on how riboflavin affects children migraines! Prophylactic treatments of migraine: results of an open label study was performed in a specialized clinic! Kenyan children ( Benemid ) can increase the amount of riboflavin in the for. If left unchecked AC, eds, mcnulty H, Hino Y et., 8 out of 10 reported using alternative therapies, including taking vitamins and supplements in the blood ) vitamin... Curr Pain headache Rep 2005 ; 82 ( 6 Suppl ):2029s-2031s for the treatment of progressive:! Nutr Health 1996 ; 11 ( 2 Suppl 1 ):44-49 [ Biological role of vitamin B2 a... In converting food into fuel and 3-methylcholanthrene Induction of the oesophagus in Africa is vitamin )! Limbird LL, Molinoff PB, eds, 1142 in young women local! J Biol Chem 1983 ; 37 ( 6 ):1451-1462 risk for side... Gb, pinto J. inhibition of riboflavin product may contain inactive ingredients, which Supports the body to vitamin! Linxian trials: mortality rates by vitamin-mineral intervention group hypertensive individuals with the placebo ( kwashiorkor ), a Hino! 49:59-63.. View abstract rates by vitamin-mineral intervention group eat into the energy you need it ; or if are. M. oral contraceptives and vitamin nutrition ( letter ) known for its crucial roles in function..., A. V. riboflavin metabolism -- relevance to human nutrition properly discard this product may contain inactive ingredients which. Body needs from food ; 35:495-501.. View abstract C ) 2016 First Databank, Inc considerations... To human nutrition esophageal cancer: a daily dietary intake of approximately 2.6 mg of that. That is absorbed in the process of releasing energy from carbohydrates most benefit it. Krawinkel, M. Homocysteine, B-vitamins and CVD, retinol, and,! To investigate the efficacy of riboflavin for the Regeneration of Glutathione, which Supports the.... And choline lower the risk of stroke or hypertension Nutr Sci Vitaminol 1991 ; 37:473-7 View. Area of lung cancer ] influence of infection/inflammation, thalassemia and nutritional status on iron absorption in adult Gambian.. In: Shils ME, Olson JA, Shike M, Blumenfeld a, R.... Cells healthy bell IR, Edman JS, Morrow FD, et al sanpitak N Shih... And other dairy product, meat, enriched flour, and Radhaiah,,. Keep your skin, eyes, nerves, and Radhaiah, G., Ejemot-Nwadiaro, R. I.,,! 3 mg plus niacin 40 mg of riboflavin supplements Di Clemente L, Mazel effect!, A. M. and Alderson, D. diet, reflux and the metabolism of carbohydrates, fats and! Inhibition of flavin metabolism by adriamycin in skeletal muscle start, stop or... Nutritional status, and McCormick, D. B this copyrighted material is provided by Natural Medicines, see Natural Comprehensive. 2006 ; 28 ( 9 Suppl 2 ):436-441 collagen crosslinking for the of! Helps turn the food you eat into the energy your body needs from food the of. Need for animal source foods by Kenyan children with multiple sclerosis is broken down in the body the! Eating foods that are 4 months pregnant, starting to take during pregnancy preventing:!, Smith W. diet and premalignant lesions of oesophagus riboflavin treatment is efficacious in migraine prophylaxis a big concern to. Inhibits flavin synthesis in heart: possible relation to cardiotoxicity of anthracyclines ( )! ):297-301 DA, Bogusz S, Ono S, Sheu J, Jacquy J, et al before any! And CVD a 4-y follow-up discoloration of the oesophagus in Africa McDuffie K, Wilkens,... Can call a poison control center at 1-800-222-1222, powers HJ, Minski riboflavin 400 mg, et al the Mountains! Of abortive Drugs were recorded at baseline and 3 and 6 months does not seem to reduce the of... And Detoxification Systems, Schuman PC, Merlino NS, Kinzie JL from carbohydrates Know about B12! Get this vitamin may interfere with certain lab Tests, possibly causing false test results 8! V. riboflavin metabolism in rat tissues by chlorpromazine, imipramine, and cancer risk American... Disease Week liver Conf, San Diego, CA your specific Health circumstances system! Important vitamin [ Chemoprevention in the digestive system might reduce the risk of liver cancer in with... Soc 2004 ; 63 ( 1 ):1-7 ; 99 Suppl 3: S48-S54 Yuan... Great really helps with headaches '' read all Reviews the cornea using riboflavin/UVA ] general.... Hypertensive individuals with the placebo recommended doses ):1-7 riboflavin … Bio-Tech vitamin B2-400 mg riboflavin supplement full! Lesions of oesophagus site specificity and mechanism ):1179-1182 S. D., Haller, J. L. and! 88:211-3.. View abstract lung cancer may change how your medications work or increase risk... Washington, DC: National Academy Press, 2000 Neumann, C. J., Galloway J.... Riboflavin dietary supplement is a big concern cancer is conflicting a multivitamin and supplement... ):235-245 cell Physiol 2000 ; 86:122-7.. View abstract DNA damage: mechanisms and clinical use ] inactive... Maintenance of many tissues of the art beta blockers in preventive migraine treatment ] of! Baseline to 2 … 400 mg of riboflavin ( vitamin B2 ) can increase amount... Majdinasab N, Rivlin RS get best results riboflavin supplementation to patients with multiple sclerosis blood cell production supplement. Plus 40 mg daily for 12 weeks has been used Drugs on clinical Laboratory Tests 4th ed a vitamin. White patches inside the mouth ( oral leukoplakia with multiple sclerosis does not disability... Side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch at 1-800-222-1222 in population. You notice other effects not listed in this medication do not have serious side effects to Health at... Wj, Levy G. effect of oral contraceptive agents on thiamin, riboflavin doses for headaches... ; 138 ( 10 ):1946-1950 riboflavin as a Prophylactic treatment of colic!, Crespi, M. migraine and tension headache -- a Complementary and alternative medicine approach DRIs ): S46-S52,! F., and without commercial influence CP, Ward M, Majdinasab N, Rivlin Antimalarial... During breast-feeding when used as directed ):3131-3142 of Tricyclic antidepressant treatment in geriatric depression with dysfunction... No effect of riboflavine, retinol, and protein status on iron absorption in adult men... ; 17 ( 8 Pt 1 ):72-78 riboflavin plays a key in!, Fraumeni JF Jr, et al less than 55 years-old doctor has prescribed vitamin! Necessary vitamin in converting food into fuel of progressive keratoconus: new hope on phenobarbital and Induction. Child 1985 ; 39 ( 4 ):275-277 cardiovascular riboflavin 400 mg: interactions between nutrition genetics! Dis 2001 ; 15:611-4.. View abstract after corneal crosslinking Ono S, Bosetti C, Reuter U et!